Close
  Indian J Med Microbiol
 

Figure 1: (a) Hematoxylin and eosin staining of the patient's laryngeal tumor at × 200 demonstrates collections of adipocytes disrupted by ropy, cellular fibrous bands punctuated by monomorphic spindle cells. (b) Immunostains (not pictured) are positive for CD34 and negative for smooth muscle actin, desmin, and S-100 protein. Fluorescence in situ hybridization demonstrates greater than 10 MDM2 signals per cell, consistent with gene amplification

Figure 1: (a) Hematoxylin and eosin staining of the patient's laryngeal tumor at × 200 demonstrates collections of adipocytes disrupted by ropy, cellular fibrous bands punctuated by monomorphic spindle cells. (b) Immunostains (not pictured) are positive for CD34 and negative for smooth muscle actin, desmin, and S-100 protein. Fluorescence <i>in situ</i> hybridization demonstrates greater than 10 MDM2 signals per cell, consistent with gene amplification