• Users Online: 64
  • Print this page
  • Email this page
CASE REPORT
Year : 2019  |  Volume : 2  |  Issue : 1  |  Page : 5-8

Biphenotypic sinonasal sarcoma: An infrequent neoplasm with classical clinical presentation and mimetic histology. Report of two cases


1 Pathology Department, Complejo Hospitalario Metropolitano C. S. S, Panama, Florida, USA
2 Department Anatomic Pathology, University of Rome Tor Vergata, Rome, Italy
3 Istituto Nazionale Tumori Regina Elena, Rome, Italy

Correspondence Address:
Marina Pacheco
Pathology Department, Complejo Hospitalario Metropolitano C.S.S, Panama, Florida
USA
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/JHNP.JHNP_2_20

Rights and Permissions

Biphenotypic sinonasal sarcoma (BSNS) is a rare low-grade sarcoma that occurs mainly in the upper sinonasal tract of middle-aged women. It exhibits a dual immunophenotype characterized by the expression of neural and myogenic markers. It is characterized by PAX3 rearrangement with various fusion partners, being MAML3 the most frequent. BSNS is a locally aggressive neoplasm, with frequent local recurrences but no metastasis reported. Here, we present the clinical, histological, immunohistochemical, and molecular findings of two new cases of BSNS that fulfill the canonical demographic, clinical, morphologic, and molecular criteria described for this infrequent entity.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed240    
    Printed0    
    Emailed0    
    PDF Downloaded31    
    Comments [Add]    

Recommend this journal